This study presents a popular science review and practical recommendations for supporting the psychological well-being of young people aged 18–35 in the CIS countries, with a focus on Russia and Kazakhstan. It is based on scientific literature and the guidelines of WHO/mhGAP, LIVE LIFE, Doing What Matters in Times of Stress, UNESCO/IESALC, and UNICEF/UNFPA (2020–2025), as well as recent meta-reviews on physical activity, sleep, and digital interventions.

The goal of this study is to synthesize the theoretical foundations of the concept of well-being (Ryff’s model, Diener’s subjective well-being model, and PERMA) with current epidemiological trends and translate them into a three-tier package of recommendations: for general practitioners (GPs), university psychologists, and young people themselves.

This methodological review combines an analysis of international initiatives in such areas as suicide prevention, the integration of brief psychosocial interventions at the PHC level, and multi-step models of assistance in educational institutions, with the regional context — including regulatory documents and programs from Russia and Kazakhstan, the development of youth health centers, and intersectoral mental health promotion and suicide prevention projects.

At the PHC tier, it highlights routine screenings (PHQ-2/9, GAD-2/9, suicide risk assessment), brief structured interventions (behavioral activation, problem-solving, PM+, WHO-guided self-help), rational pharmacotherapy according to the 2023 mhGAP updates, and “movement prescription” and sleep hygiene counseling as therapeutic modules.

This review proposes a multi-step service model for universities (awareness → brief consulting protocols → referral), the introduction of digital interventions (iCBT, blended approaches), and regular well-being monitoring and crisis protocols. For young people, it formulates a “survival kit”: a target dose of physical activity (≥150 min/week), a 7–9-hour sleep schedule, daily stress management practices according to WHO guidelines, and clear criteria for seeking professional help.